Photometrics Prime BSI Express sCMOS Camera

• 95% Quantum Efficiency
• 6.5µm x 6.5µm Pixel Area
• 1.0e- Read Noise

Product Description

High Resolution BSI Scientific CMOS

The Prime BSI Express Scientific CMOS (sCMOS) is designed on a compact platform optimized for integration and delivers the perfect balance between high resolution imaging and sensitivity with an optimized pixel design, USB 3.2 Gen 2 connectivity and near perfect 95% Quantum Efficiency to maximize signal detection.


By bringing the light in from the back of the sensor, photons land directly onto the light receiving surface, maximizing light collecting capability.

The Prime BSI Express combines 95% quantum efficiency with the low 1.0 e- read noise CMS mode to deliver the most sensitive camera based on sCMOS technology at over 40 frames per second.



Compact Form Factor

The Prime BSI Express is a compact 78mm x 78mm x 90mm with optimized cooling for the size, ideal for integration into new or existing configurations.


Resolution and Pixel Size

The Prime BSI Express features 6.5 µm pixels, the accepted standard for most live cell applications.

This pixel size provides highly detailed images across the imaging plane and is most suitable for the broadest range of magnifications.

Prime BSI Express Data Sheet Prime BSI Express Manual Get a Quote Comparisons Back to sCMOS Cameras

Additional information


• Sensor – Gpixel GSENSE2020BSI Scientific CMOS sensor
• Active Array Size – 2048 x 2048 (4.2 Megapixel)
• Pixel Area – 6.5μm x 6.5μm (42.25μm2)
• Sensor Area – 13.3mm x 13.3mm – 18.8mm diagonal
• Peak QE% – >95%
• Read Noise – 1.6e- (Median) – 1.8e- (RMS)
• Full-Well Capacity – 45,000e- (Combined Gain), 10,000e- (High Gain)
• Dynamic Range – 35,000:1 (Combined Gain)
• Bit Depth – 16-bit (Combined Gain), 11-bit (High Gain)
• Readout Mode – Rolling Shutter – Effective Global Shutter
• Binning – 2×2 (on FPGA)

Key Camera Features

• 95% Quantum Efficiency
• 6.5µm x 6.5µm Pixel Area
• 2048 x 2048 array – 4.2 Megapixel
• 1.0e- Read Noise
• 45,000e- Pixel Full Well
• 35,000:1 Dynamic Range
• 43.5fps @ 16-bit
• 63fps @ 11-bit

Primary Applications

• TIRF Microscopy
• Ratiometric Imaging
• Cell Motility
• Light Sheet Microscopy


Cooling Performance

Air Cooled
Liquid Cooled

Sensor Temperature

-20ºC @ 30ºC Ambient
-30ºC @ 30ºC Ambient

Dark Current



Digital Interface
Lens Interface
Mounting Points
Liquid Cooling

Camera Interface

PCIe, USB 3.0
2 x ¼ 20” mounting points per side to prevent rotation
Quick Disconnect Ports

Triggering Mode

Input Trigger Modes Trigger-First:


Output Trigger Modes Any Row:


Output Trigger Signals


Sequence triggered on first rising edge
Edge: Each frame triggered on rising edge
SMART Streaming: Fast iteration through multiple exposure times

Expose signal is high while any row is acquiring data
Rolling Shutter: Effective Global Shutter – Expose signal is high when all rows are acquiring data
Signal is High for set Exposure time – Readout Time

Expose Out (up to four signals), Read Out, Trigger Ready