Alvéole Primo 2

Alvéole Primo 2

The Alveole Primo system provides micropatterning, hydrogel polymerization and microfabrication, all in a single device. It is designed to create bespoke in vitro cellular microenvironments and get better cell models for your cell biology experiments or cryo-ET studies.

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Alvéole Primo 2

PRIMO 2 is new generation hardware with compact footprint, new optical design allowing epi-fluorescence microscopy and faster performance.

Developed by Alvéole scientists after the LIMAP* technology (Strale P.O. et al, Adv Mater. 2016), the PRIMO maskless photopatterning system (DMD based) can engineer custom in vitro cell microenvironments through three techniques: micropatterning, hydrogel structuration and microfabrication.

PRIMO bioengineering technology

Developed by Alvéole scientists after the LIMAP* technology (Strale P.O. et al, Adv Mater. 2016), the PRIMO maskless photopatterning system (DMD based) can engineer custom in vitro cell microenvironments through three techniques: micropatterning, hydrogel structuration and microfabrication.

PRIMO workflow for better in vitro cell models: 

  1. Substrate selection and preparation
  2. Pattern Design and upload in Leonardo software
  3. UV Projection by Primo for micropatterning, microfabrication, hydrogel polymerization
  4. Using Custom in vitro Conditions 

Application Usage

  • Micropatterning
    PRIMO micropatterning system allows to fine-tune cell adhesion to mimic in vivo phenotypes, study cellular mechanisms or isolate cells in reproducible conditions for standardized assays.
  • Microfabrication
    PRIMO DMD-based photopatterning system can perform greyscale photolithography on greyscale resists to create complex 3D moulds such as ramps, curving wells or microfluidic chips for organ-on-a-chip applications.
  • Hydrogels
    As a photopatterning system, PRIMO can also polymerize and photo-scission most commonly used hydrogels for 3D cell culture, spheroid formation or polymerizing permeable membranes in microfluidic chips.

Features and Benefits

  • Micropatterning
  • Microfabrication
  • Hydrogels

Research Examples

Coming Soon!

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FAQ

Cairns’s design ethos is based on compatibility across a wide range of manufacturers. In the rare case where we do not have a compatible part, we have a custom design team available to provide a solution. 

We provide a comprehensive 12-month warranty on all our products.

We aim for a delivery time of 2-4 weeks. However, the specific delivery time will be confirmed at the point of order.

We offer full training and support across our entire product range. 

Yes, we have full custom design capabilities and a multidisciplinary team of scientists and engineers available to provide a solution that meets your needs. 

Our CellCams are supported in Micro-Manager and we have a full SDK available. 

Customer Reviews

"The build quality of their equipment is excellent, and has proven both reliable and versatile in our lab’s day-to-day research; our Cairn equipment has provided years of dependable service."
Andrew James
“Over the past 20 years we have purchased a wide range of equipment from Cairn Research, ranging from several Optopatch amplifiers, OptoLED, Optosourse arc lamp and custom-made optical pathways for nanoscale measurements.”
Walter Marcotti
“What I love about this company is the quality and the reliability of every piece of equipment that I purchased. The instruments are made of high-grade materials (mostly aluminum for the optics components) and are intended for heavy everyday use in the laboratory. “
Andreas Werdich

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